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How Does Garcinia Cambogia Work? There?s a phytochemical found in Garcinia, called hydroxycitric acid (HCA), and it has a dual effect on supporting weight loss. (1) HCA has the ability to reduce appetite by way of increasing serotonin levels in the brain. Serotonin is a neurotransmitter that affects mood and sleep patterns. Increasing serotonin levels has been shown to decrease food intake, enhance mood, and reduce weight gain. (2) HCA can support weight loss by inhibiting an enzyme called ATP-citrate-lyase (ACL). This enzyme helps convert excess carbohydrates (sugars) into fat in the body. When HCA inhibits ATP-citrate-lyase, fat buildup and storage is blocked in the body. GARCINIA CAMBOGIA 1500 delivers a 80% HCA extract, which is the highest percentage commercially today! Reduces Appetite Blocks Fat Build-Up & Storage Supports Weight Loss